ELISA CRHR1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Corticotropin releasing factor type 1 receptor antibody; corticotropin releasing hormone receptor 1 antibody; Corticotropin-releasing factor receptor 1 antibody; Corticotropin-releasing hormone receptor 1 antibody; CRF R antibody; crf receptor 1 antibody; crf receptor type 1 antibody; crf type 1 antibody; CRF-R antibody; CRF-R-1 antibody; CRF-R1 antibody; CRF1 antibody; CRFR antibody; CRFR-1 antibody; CRFR1 antibody; CRFR1_ antibody; CRH-R-1 antibody; CRH-R1 antibody; CRH-R1h antibody; CRHR antibody; Crhr1 antibody; CRHR1f antibody; CRHR1L antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P34998 Immunogen:Recombinant Corticotropin-releasing factor receptor 1 protein (24-121AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellµLar cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimµLi. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CRHR1 Research Areas:Neuroscience; Cancer; Metabolism; Signal transduction